Addition of metronidazole to cefazolin for antibiotic prophylaxis at hysterectomy: a weighted analysis

After weighting based on preoperative characteristics, the addition of metronidazole to cefazolin for prophylaxis at the time of hysterectomy did not significantly decrease the probability of developing SSI compared to cefazolin alone. Any regimen of antibiotics other than cefazolin or cefazolin with metronidazole was associated with increased probability of SSI.

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Publication Details

Journal
Minerva Obstetrics and Gynecology
Published
2025-09-03
DOI
https://doi.org/10.23736/s2724-606x.25.05728-8
Citations
1
Primary Topic
Surgical site infection prevention
Type
article
Field-Weighted Citation Impact
2.01
Controls
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article

Addition of metronidazole to cefazolin for antibiotic prophylaxis at hysterectomy: a weighted analysis

David Sheyn, Elisa Simona Marra, H Bauer, Stephen Rhodes et al.
1 citations
Minerva Obstetrics and Gynecology
Surgical site infection prevention
2.01
article

Addition of metronidazole to cefazolin for antibiotic prophylaxis at hysterectomy: a weighted analysis

David Sheyn, Elisa Simona Marra, H Bauer, Stephen Rhodes, Leila S Hojat, Adonis K. Hijaz
article en
1 citations

Abstract

After weighting based on preoperative characteristics, the addition of metronidazole to cefazolin for prophylaxis at the time of hysterectomy did not significantly decrease the probability of developing SSI compared to cefazolin alone. Any regimen of antibiotics other than cefazolin or cefazolin with metronidazole was associated with increased probability of SSI.

Minerva Obstetrics and GynecologyVol. 78(1)
University Hospitals of Cleveland (US), University Hospitals Cleveland Medical Center (US)
Openalex Percentile: Top 12%
Surgical site infection prevention
2.01
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