Asymptomatic Troponin Elevation and Early Mortality Following Immune Checkpoint Inhibitor Therapy in Patients Without Cardiac Adverse Events

Subclinical troponin elevation is common in patients treated with ICIs. Higher troponin levels may be associated with earlier death; however, the underlying mechanisms remain unclear. Careful interpretation is needed and further research is required to clarify its prognostic value.

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Publication Details

Journal
Cancer Diagnosis & Prognosis
Published
2025-09-01
DOI
https://doi.org/10.21873/cdp.10479
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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article

Asymptomatic Troponin Elevation and Early Mortality Following Immune Checkpoint Inhibitor Therapy in Patients Without Cardiac Adverse Events

Takuro Imaoka, Kazuko Tajiri, Atsuko Suzuki, Yasunori Shibutani
Cancer Diagnosis & Prognosis
Cancer Immunotherapy and Biomarkers
article

Asymptomatic Troponin Elevation and Early Mortality Following Immune Checkpoint Inhibitor Therapy in Patients Without Cardiac Adverse Events

Takuro Imaoka, Kazuko Tajiri, Atsuko Suzuki, Yasunori Shibutani
article en

Abstract

Subclinical troponin elevation is common in patients treated with ICIs. Higher troponin levels may be associated with earlier death; however, the underlying mechanisms remain unclear. Careful interpretation is needed and further research is required to clarify its prognostic value.

Cancer Diagnosis & PrognosisVol. 5(5)
University of Tsukuba (JP), National Cancer Center Hospital East (JP)
Ministry of Health, Labour and Welfare, Japan Society for the Promotion of Science
Openalex Percentile: Top 67%
Cancer Immunotherapy and Biomarkers
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