Definitive Diagnosis of Angiomatoid Fibrous Histiocytoma Using Dual DNA/RNA Genomic Profiling
This case underscores the diagnostic challenges of AFH, particularly in older patients with deep-seated lesions mimicking hematomas. Dual DNA/RNA genomic profiling enabled definitive diagnosis and demonstrated its clinical utility in evaluating soft-tissue tumors with ambiguous histopathological features.
Authors
- Kenichi Kohashi (ORCID: https://orcid.org/0000-0002-2358-7452)
- Naoki Takada (ORCID: https://orcid.org/0000-0002-0423-9612)
- Naoto Oebisu
- Hidetomi Terai (ORCID: https://orcid.org/0000-0001-9183-3363)
- Hana Yao
- Ryo Nishida
Institutions
- Osaka Metropolitan University (JP)
- Tokyo Metropolitan University (JP)
Publication Details
- Journal
- Cancer Diagnosis & Prognosis
- Published
- 2025-09-01
- DOI
- https://doi.org/10.21873/cdp.10477
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00