BMP2 alterations in mucinous cystadenocarcinoma of the breast: insights from whole-exome sequencing

This study provides new insights into the clinical and molecular features of breast MCA, suggesting that tumor stage is an important prognostic indicator. BMP2 emerged as a potential driver of tumor progression, and its utility as a predictive or prognostic biomarker warrants further investigation in larger cohorts. These findings may pave the way for improved prognostic assessment and novel therapeutic strategies targeting BMP2 in breast MCA.

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Publication Details

Journal
PeerJ
Published
2025-09-03
DOI
https://doi.org/10.7717/peerj.19948
Primary Topic
Breast Lesions and Carcinomas
Type
article
Field-Weighted Citation Impact
0.00
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article

BMP2 alterations in mucinous cystadenocarcinoma of the breast: insights from whole-exome sequencing

Qingming Jiang, Juanhui Dong, Zhenyu Li, Rui Chen et al.
PeerJ
Breast Lesions and Carcinomas
article

BMP2 alterations in mucinous cystadenocarcinoma of the breast: insights from whole-exome sequencing

Qingming Jiang, Juanhui Dong, Zhenyu Li, Rui Chen, Yi Gong, Guangxin Li
article en

Abstract

This study provides new insights into the clinical and molecular features of breast MCA, suggesting that tumor stage is an important prognostic indicator. BMP2 emerged as a potential driver of tumor progression, and its utility as a predictive or prognostic biomarker warrants further investigation in larger cohorts. These findings may pave the way for improved prognostic assessment and novel therapeutic strategies targeting BMP2 in breast MCA.

PeerJVol. 13
Chongqing University (CN), Chongqing Cancer Hospital (CN)
Openalex Percentile: Top 66%
Breast Lesions and Carcinomas
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BMP2 alterations in mucinous cystadenocarcinoma of the breast: insights from whole-exome sequencing — Qingming Jiang, Juanhui Dong, et al. · PeerJ (2025) | TGRS Research Map | TGRS