Binding differences of fluxapyroxad with succinate dehydrogenase across species: insights from <i>in silico</i> simulations
The binding differences of FLX with SDH across species might be attributed to the π-π interaction provided by SDHC tryptophan. This study revealed the probable binding modes of FLX with SDH, which might facilitate the future design of selective SDHIs. © 2025 Society of Chemical Industry.
Authors
- Na Zhai
- Jiagao Cheng (ORCID: https://orcid.org/0000-0001-5355-4566)
- Cong Zhou (ORCID: https://orcid.org/0000-0002-0627-4593)
- Zhong Li (ORCID: https://orcid.org/0000-0001-6665-5040)
- Xiaoyong Xu (ORCID: https://orcid.org/0000-0003-3481-3977)
- Liangliang Cheng (ORCID: https://orcid.org/0009-0009-8274-2721)
Institutions
- East China University of Science and Technology (CN)
Publication Details
- Journal
- Pest Management Science
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1002/ps.70191
- Citations
- 1
- Primary Topic
- Fungal Plant Pathogen Control
- Type
- article
- Field-Weighted Citation Impact
- 3.03
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China