Integrated Single-Cell and Transcriptome Analysis with Experimental Validation Reveals PANoptosis-Related Gene Signatures in the Immune Microenvironment of Autoimmune Thyroiditis
In summary, our study reveals the characteristics of the immune microenvironment of AIT and highlights the clinical potential of PANoptosis-Related genes (AIM2, ZBP1, NLRP6, MLKL, and FAS) as diagnostic biomarkers.
Authors
- Nan Song (ORCID: https://orcid.org/0000-0002-2495-8251)
- Hao Gao (ORCID: https://orcid.org/0000-0003-1178-0121)
- Qun Wang (ORCID: https://orcid.org/0000-0003-4853-1727)
- Ziyu Liu (ORCID: https://orcid.org/0000-0001-7149-4827)
- Xiao Yang (ORCID: https://orcid.org/0000-0002-5150-7341)
- Zhuo Zhao (ORCID: https://orcid.org/0000-0003-0907-3620)
Institutions
- Liaoning University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/jir.s525270
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81