The Role of Plasma Metabolites in Mediating the Effect of Gut Microbiota on Obstructive Sleep Apnea: A Two-Step, Two-Sample Mendelian Randomization Study
The study highlighted the protective effect of species Parabacteroides merdae against OSA. It also revealed the mediating role of 2-hydroxypalmitate in the relationship between species Parabacteroides merdae and OSA.
Authors
- Kezhen Yang (ORCID: https://orcid.org/0000-0003-2469-1494)
- Xiaona Wang (ORCID: https://orcid.org/0000-0001-8054-1445)
- Bo Xu (ORCID: https://orcid.org/0000-0002-9102-5128)
- Jia Guo (ORCID: https://orcid.org/0000-0001-8454-8951)
- Ranran Zhao
Institutions
- Capital Medical University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Nature and Science of Sleep
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/nss.s527778
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Friendship Hospital, Capital Medical University