Selective IgM digestion improves anti-AAV IgG detection in the immune complex assay format

Co-existing anti-AAV IgM cause interference in the anti-AAV IC assay format. Selective IgM digestion improves the detection of anti-AAV IgG in the IC assay.

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Publication Details

Journal
Bioanalysis
Published
2025-08-18
DOI
https://doi.org/10.1080/17576180.2025.2548191
Citations
1
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
1.36

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article

Selective IgM digestion improves anti-AAV IgG detection in the immune complex assay format

Alexander Pöhler, Francesca Ros, Uwe Wessels, Kay-Gunnar Stubenrauch
1 citations
Bioanalysis
Monoclonal and Polyclonal Antibodies Research
1.36
article

Selective IgM digestion improves anti-AAV IgG detection in the immune complex assay format

Alexander Pöhler, Francesca Ros, Uwe Wessels, Kay-Gunnar Stubenrauch
article en
1 citations

Abstract

Co-existing anti-AAV IgM cause interference in the anti-AAV IC assay format. Selective IgM digestion improves the detection of anti-AAV IgG in the IC assay.

BioanalysisVol. 17(16)
Roche (Switzerland) (CH)
Roche Diagnostics
Openalex Percentile: Top 16%
Monoclonal and Polyclonal Antibodies Research
1.36
DOIOpen Access PDFOpenAlex
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Selective IgM digestion improves anti-AAV IgG detection in the immune complex assay format — Alexander Pöhler, Francesca Ros, et al. · Bioanalysis (2025) | TGRS Research Map | TGRS