Combined Use of Peripheral Nerve Surgery and Peripheral Nerve Stimulation in Patients With Refractory Neuropathic Pain
This proof-of-concept study suggests that combined peripheral nerve surgery and PNS may be a viable option for carefully selected patients with severe, refractory neuropathic pain. While pain reduction and functional improvement were observed in most patients, outcomes varied considerably. Future prospective studies with larger cohorts are needed to refine patient selection criteria and optimize this combined approach.
Authors
- Ian L. Valerio (ORCID: https://orcid.org/0000-0001-8573-8810)
- David Hao (ORCID: https://orcid.org/0000-0002-0221-9255)
- Kyle R. Eberlin (ORCID: https://orcid.org/0000-0003-4427-2588)
- Benjamin R. Johnston (ORCID: https://orcid.org/0000-0001-5622-1257)
- Floris V. Raasveld (ORCID: https://orcid.org/0000-0002-7566-1159)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Erasmus MC (NL)
- Massachusetts General Hospital (US)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Microsurgery
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/micr.70112
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wyss Foundation