Differentiation of cisplatin uptake within a population of cancer cells – how to “crack this nut” using single-cell ICP-MS
A versatile tool to unravel the uptake diversity of a front-line anticancer drug, cisplatin, within a cancer cell population is proposed herein based on single-cell inductively coupled plasma mass spectrometry. The interested researcher is provided with a tutorial to help adapt such cutting-edge methodology and know-how to reliable data processing.
Authors
- Zuzanna Szymańska (ORCID: https://orcid.org/0000-0002-2968-5627)
- Magdalena Matczuk (ORCID: https://orcid.org/0000-0001-5631-8163)
- Andrei R. Timerbaev (ORCID: https://orcid.org/0000-0001-5249-3861)
- Agnieszka Żuchowska (ORCID: https://orcid.org/0000-0003-3516-3830)
- Maciej Jarosz (ORCID: https://orcid.org/0000-0002-8368-9274)
- Paweł Romanczuk (ORCID: https://orcid.org/0000-0001-5785-7046)
Institutions
- Warsaw University of Technology (PL)
- University of Vienna (AT)
- Medical University of Warsaw (PL)
Publication Details
- Journal
- The Analyst
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5an00152h
- Primary Topic
- Mass Spectrometry Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Politechnika Warszawska