2D Speckle Tracking Strain Echocardiography in Multisystem Inflammatory Syndrome in Children: A Multicenter Analysis From the MUSIC Study
About half of patients with MIS-C had abnormal LV strain during hospitalization. 4CH-LVLS, mid-LVCS, the most abnormal strain <i>Z</i> score, and early diastolic longitudinal strain rate at admission were independently associated with in-hospital adverse cardiovascular outcome. These data may help early characterization and prognostication in MIS-C.
Authors
- Vishnu Undyala
- Phenique Parker
- Liza‐Marie Johnson (ORCID: https://orcid.org/0000-0002-7124-979X)
- Regina Cole
- Kristen Sexson
- Martha Rolland
- Jennifer L. Howell (ORCID: https://orcid.org/0000-0001-5418-3736)
- Mitchell Haverty (ORCID: https://orcid.org/0000-0003-3611-7609)
- Gwendolyn Orav
- Shivraj Savadkar
- Anita Krishnan (ORCID: https://orcid.org/0000-0002-8662-7810)
- Kristin M. Burns (ORCID: https://orcid.org/0000-0001-8665-1303)
- Ricardo H. Pignatelli
- Michelle Hite
- Deepika Thacker (ORCID: https://orcid.org/0000-0002-6738-397X)
- Katherine Lupton
- Suchitra Rao
- Kathleen Van’t Hof
- Mary Stumpf
- J. Philip Saul
- Anna Clarke (ORCID: https://orcid.org/0000-0002-0972-1424)
- Beth Gamulka
- Hunter C. Wilson (ORCID: https://orcid.org/0000-0003-2087-7478)
- Andrea Curless
- Tamara T. Bradford (ORCID: https://orcid.org/0000-0001-5220-7423)
- Allison Crosby‐Thompson
- Chitra Kinhikar
- Jeffrey A. Kertis
- Olukayode Garuba
- Maryanne Chrisant (ORCID: https://orcid.org/0000-0002-7010-8821)
- Jami Honig
- Gautham Singh
- Tor-Samuel-Aleer Leek
- Lauryn Dugan
- Samantha Stack
- Grace Marks
- Keren Hasbani
- Aiman Almasnaah (ORCID: https://orcid.org/0000-0003-3610-0874)
- Audrey Dionne (ORCID: https://orcid.org/0000-0003-2864-1830)
- Lauren Goodell
- Jodie K. Votava‐Smith (ORCID: https://orcid.org/0000-0002-8934-5333)
- Charlotte V. Hobbs (ORCID: https://orcid.org/0000-0003-4829-0791)
- Gloria Mitscher
- Pei‐Ni Jone (ORCID: https://orcid.org/0000-0001-5145-0341)
- Carol Prospero (ORCID: https://orcid.org/0000-0003-4969-9513)
- Miriam Davis
- Moya Chang
- Raquel Conceição Ferreira (ORCID: https://orcid.org/0000-0001-8897-9345)
- Andrew S. Mackie (ORCID: https://orcid.org/0000-0001-6126-1130)
- Michael R. Carr (ORCID: https://orcid.org/0000-0003-0345-0341)
- Maria Martinez (ORCID: https://orcid.org/0000-0003-3799-3360)
- Joe Block
- Brian Hannah
- Chesney Castleberry (ORCID: https://orcid.org/0000-0002-9052-2333)
- Onyekachukwu Osakwe (ORCID: https://orcid.org/0000-0001-6079-1850)
- Madelyn R. Barr
- Mayra Lemus Rangel
- Kerri Hayes
- Brian W. McCrindle (ORCID: https://orcid.org/0000-0001-6485-6551)
- Kay Rubio
- Djenawa Bowman
- Sarah Litt (ORCID: https://orcid.org/0009-0003-7378-3181)
- Karen Martyrosyan
- Asela Liu
- Faridis Serrano (ORCID: https://orcid.org/0000-0003-3586-1671)
- Kathleen Rathge
- Kolby Sanders-Lewis
- Elizabeth Mitchell (ORCID: https://orcid.org/0000-0002-2830-1978)
- Cole Gallagher
- Charles I. Berul (ORCID: https://orcid.org/0000-0002-9604-7369)
- Todd Nowlen (ORCID: https://orcid.org/0000-0001-9615-6138)
- Lozan Eyob
- Megan Warner
- Michael D. Taylor (ORCID: https://orcid.org/0000-0003-0251-8017)
- Parvin Mohazabnia
- Craig S. Broberg (ORCID: https://orcid.org/0000-0002-9797-9803)
- Caitlen Taylor
- Candace M. Howard (ORCID: https://orcid.org/0000-0001-6537-3551)
- Lerraughn Morgan (ORCID: https://orcid.org/0000-0001-7144-9110)
- Paulette Smith
- Ken Shaffer
- Shubhika Srivastava (ORCID: https://orcid.org/0000-0002-8206-431X)
- Jyoti Patel (ORCID: https://orcid.org/0000-0002-6919-5032)
- Thor Thorsson
- Linda M. Lambert (ORCID: https://orcid.org/0000-0002-4334-700X)
- Jennifer Maldonado (ORCID: https://orcid.org/0000-0002-4909-5237)
- Fraser Golding (ORCID: https://orcid.org/0000-0002-4375-4094)
- Beverly Slayton
- Rae S. M. Yeung (ORCID: https://orcid.org/0000-0003-2361-725X)
- Mark Payne
- Pierre C. Wong (ORCID: https://orcid.org/0000-0003-3794-5887)
- Lauren DiStefano
- Amy J. Wagoner Johnson (ORCID: https://orcid.org/0000-0001-8396-3803)
- Victoria L. Pemberton (ORCID: https://orcid.org/0000-0001-5610-9070)
- Yamuna Sanil
- Rachel Downey (ORCID: https://orcid.org/0000-0001-9275-8879)
- Ashraf S. Harahsheh (ORCID: https://orcid.org/0000-0002-2622-573X)
- Camden L. Hebson (ORCID: https://orcid.org/0000-0002-6484-0629)
- Patrick McGeoghegan (ORCID: https://orcid.org/0000-0002-6065-2938)
- Lilly Fagatele
- Lisa Pomeroy
- Numaira Khan
- Thomas Giorgio
- Jade Porche
- Doris Alaby
- Michelle Sykes
- Susie Gentry
- Ryan Shea (ORCID: https://orcid.org/0000-0002-8213-2036)
- Kristin Lanzilotta
- Stephanie S. Handler (ORCID: https://orcid.org/0000-0002-4114-599X)
- Katheryn Crane
- Matthew E. Oster (ORCID: https://orcid.org/0000-0002-2243-8367)
- Jane W. Newburger (ORCID: https://orcid.org/0000-0002-7794-9017)
- Andrew L. Cheng (ORCID: https://orcid.org/0000-0002-4860-6218)
- Chenwei Hu
- Danielle Katz (ORCID: https://orcid.org/0000-0002-1907-0338)
- Ashley Herzberg
- Francesca Sperotto (ORCID: https://orcid.org/0000-0001-7109-0582)
- Aren E. Worrell
- Therese M. Giglia (ORCID: https://orcid.org/0000-0002-1571-6330)
- Kevin G. Friedman (ORCID: https://orcid.org/0000-0002-3180-9764)
- Tiffany Bowie
- Deepthi G. Nair
- M. David Weiland (ORCID: https://orcid.org/0009-0009-4952-2874)
- James Ambrosoli
- Carl Owada
- Scott Pletzer (ORCID: https://orcid.org/0000-0001-5732-6261)
- Ryan Serrano (ORCID: https://orcid.org/0000-0002-7759-8106)
- Joan Pancheri
- Cassandra Artis
- William T. Mahle (ORCID: https://orcid.org/0000-0003-1065-3972)
- Devine Mbiydzenyuy
- Joshua Germann
- Christopher Wai Kei Lam (ORCID: https://orcid.org/0000-0003-3994-2030)
- Lazaros K. Kochilas (ORCID: https://orcid.org/0000-0002-4686-634X)
- Paul H. Lipkin (ORCID: https://orcid.org/0000-0002-9043-2581)
- Mikayla A. Beckley (ORCID: https://orcid.org/0000-0003-3584-3991)
- Jessica Bainton (ORCID: https://orcid.org/0000-0002-3870-9651)
- Amanda Marshall
- Norma Barton
- Tonia Morrison
- Annette Baker (ORCID: https://orcid.org/0000-0002-8632-5994)
- Dongngan T. Truong (ORCID: https://orcid.org/0000-0002-1783-6061)
- Daniel Forsha (ORCID: https://orcid.org/0000-0003-1999-6509)
- Ed Marcus
- Alissa Mooney
- Dianne L. Atkins (ORCID: https://orcid.org/0000-0001-6123-3105)
- Chantal Sanchez
- Olga Shamailova
- Patrick S. McQuillen (ORCID: https://orcid.org/0000-0002-8837-364X)
- Kirsten Dummer (ORCID: https://orcid.org/0000-0001-9484-4770)
- Marisa Almaguer
- Robin Rowe
- Megan M. Bickford
- Tammy Doman
- Michael A. Portman (ORCID: https://orcid.org/0000-0002-8168-3725)
- Michael C. Spaeder (ORCID: https://orcid.org/0000-0002-6175-8435)
- Hidemi Kajimoto (ORCID: https://orcid.org/0000-0003-2624-7928)
- Heather Williams (ORCID: https://orcid.org/0000-0003-0755-3866)
- Rob Nero
- Preeti Vemula
- Wendy Rojas
- Eduardo Saad (ORCID: https://orcid.org/0000-0002-8879-9077)
- Zachary White
- Ayesha Amarnath
- Sindhu Mohandas (ORCID: https://orcid.org/0000-0002-8397-6249)
- Lara Shekerdemian (ORCID: https://orcid.org/0000-0002-6608-9832)
- Jemylle Grace S. Morato
- Julie Miller (ORCID: https://orcid.org/0009-0001-6345-585X)
- Laura Olivieri
- Isaura Macias
- Alix Fetch
- Melissa Joyce
- Varsha Zadokar
- Dana Albizem
- Kimberly E. McHugh (ORCID: https://orcid.org/0000-0001-8329-5411)
- Kristal M. Hock (ORCID: https://orcid.org/0000-0002-4301-3616)
- Heather Heizer
- Carol McFarland (ORCID: https://orcid.org/0000-0002-4894-9704)
- Patti Walter
- Charmaine Williams-Farr
- Brooke DiGiovanni Evans (ORCID: https://orcid.org/0000-0001-7461-7271)
- Nancy Sullivan (ORCID: https://orcid.org/0000-0003-1244-4074)
- Arash Sabati (ORCID: https://orcid.org/0000-0002-8146-6819)
- Jennifer Su (ORCID: https://orcid.org/0000-0002-7749-0912)
- Lisa Jean Buckley
- Sujatha Buddhe (ORCID: https://orcid.org/0000-0001-8709-4051)
- Sandra Tyler
- Jogarao Gobburu (ORCID: https://orcid.org/0000-0002-8348-4295)
- Katherine Hildebrand
- Brett R. Anderson (ORCID: https://orcid.org/0000-0002-0450-9387)
- Melissa S. Burnett
- Emily Birmingham
- Sean M. Lang (ORCID: https://orcid.org/0000-0002-4804-8789)
- Aimee S. Parnell (ORCID: https://orcid.org/0000-0001-9574-7411)
- Sally Hunsberger (ORCID: https://orcid.org/0000-0002-4251-5622)
- Kanwal M. Farooqi (ORCID: https://orcid.org/0000-0002-6708-0119)
- Jacob Strelow
- Isabel Glassmeyer
- Mark W. W. Russell (ORCID: https://orcid.org/0000-0003-4855-9260)
- Elle Seibert (ORCID: https://orcid.org/0000-0001-6262-3965)
- Kristie Le
- Matthew D. Elias (ORCID: https://orcid.org/0000-0002-9534-2809)
- Marla Johnston (ORCID: https://orcid.org/0000-0003-3831-7946)
- Divya Shakti (ORCID: https://orcid.org/0000-0003-1399-924X)
- Felicia Trachtenberg
- Madison Rudow
- Rachel Amsellem
- David P. Gordy
- Valiantsina Kazlova
- D’Andrea Freemon
- Shuo Wang (ORCID: https://orcid.org/0000-0001-9104-9798)
- Mo Zhang (ORCID: https://orcid.org/0000-0003-3231-5915)
- Susan Park (ORCID: https://orcid.org/0000-0002-7082-8554)
- Jessica Jones (ORCID: https://orcid.org/0000-0002-7652-2601)
- Jennifer C. Nelson (ORCID: https://orcid.org/0000-0002-2968-2661)
- F.J. Evans
- Andrew J. Powell
- Kavita Sharma
- Juan Carlos Muniz
- Edward J. Williams (ORCID: https://orcid.org/0000-0003-0240-831X)
- Andréea Dragulescu
- Madison Johnson
- LaTina Watson
- David J. Driscoll
- Mary Sue McCall
- Christina Schott
- Thomas J. Knight
- Colleen Sullivan
- Sandra Peña
- Sanjeev Aggarwal
- Donna Sylvester
- Simran Mahanta
- Gail Pearson
- Joseph Block
- PJ Mu
- Lynn Mahony (ORCID: https://orcid.org/0000-0003-3610-4410)
- Nancy Kehlenbrink
- Amy Ellerbe
Institutions
- Northwestern University (US)
- Children's Hospital of Wisconsin (US)
- Cincinnati Children's Hospital Medical Center (US)
- George Washington University Hospital (US)
- Boston Children's Hospital (US)
- Primary Children's Hospital (US)
- Children's Mercy Hospital (US)
- Children's Hospital of Philadelphia (US)
- Children's National (US)
- Children's Hospital of Los Angeles (US)
- Emory University (US)
- Medical University of South Carolina (US)
- Palo Alto University (US)
- Baylor College of Medicine (US)
- Columbia University Irving Medical Center (US)
- Hospital for Sick Children (CA)
- Riley Hospital for Children (US)
- University of Mississippi Medical Center (US)
- University of Mississippi (US)
- Rady Children's Hospital-San Diego (US)
- Community Care (US)
- Dell Children's Medical Center of Central Texas (US)
- Nemours Children's Health System (US)
- Cohen Children's Medical Center (US)
- Children's Hospital of New Orleans (US)
- Phoenix Children's Hospital (US)
- Mercy Hospital (US)
- Children's Hospital of Michigan (US)
- Texas Children's Hospital (US)
- C. S. Mott Children's Hospital (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Columbia University (US)
- Stanford University (US)
Publication Details
- Journal
- Circulation Cardiovascular Imaging
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1161/circimaging.124.017620
- Citations
- 1
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 2.01