Evaluation and Research Progress of Neonatal Ventilator Weaning Strategies

With the continuous advancement of neonatal intensive care technology, mechanical ventilation has become an important means of neonatal respiratory support therapy. Prolonged mechanical ventilation can lead to ventilator-related problems, lung injury, respiratory muscle fatigue, etc., increasing the incidence of chronic lung disease and the risk of death in neonates; premature weaning can easily lead to weaning failure and increase the risk of re-intubation or repeated intubation. Rationally assessing the timing of weaning and formulating a scientific weaning strategy have become important issues in the management of neonatal respiratory support. This article systematically reviews the latest research progress on the main factors affecting the success of neonatal weaning, clinical evaluation methods, and weaning strategies, aiming to provide evidence-based support for clinicians, optimize the weaning process, improve the success rate of weaning, reduce the occurrence of related complications, and improve neonatal prognosis.