Modulation of <i>P. aeruginosa</i> quorum sensing and host immune response with biomimetic cyclodextrin enzyme models
Thiol and Cu( ii ) bearing cyclodextrin derivatives mimicking the active sites of lactonases and cysteine hydrolases are shown to modulate bacterial quorum sensing, reduce pro-inflammatory cytokine and mucin expression of infected lung cells.
Authors
- Sündüs Erbaş-Çakmak (ORCID: https://orcid.org/0000-0003-4168-8377)
- Safaa Altveş (ORCID: https://orcid.org/0000-0001-5873-2085)
- Emrah Kavak (ORCID: https://orcid.org/0000-0002-6161-2030)
- Nezahat Gokce Ozsamur (ORCID: https://orcid.org/0000-0003-0866-9617)
Institutions
- Necmettin Erbakan University (TR)
Publication Details
- Journal
- Materials Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ma00162e
- Primary Topic
- Bacterial biofilms and quorum sensing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
- Türkiye Bilimler Akademisi