Lesion‐Based Disconnectome Explains Cognitive Outcomes in Multiple Sclerosis
Lesion-driven disconnection is a more robust determinant of cognitive impairment in MS than lesion burden alone, and disconnectome mapping may help understand the indirect network-level mechanisms underlying cognitive deficits in MS.
Authors
- Francesco La Rosa (ORCID: https://orcid.org/0000-0002-9224-4664)
- Fernanda Cristina Rueda Lopes (ORCID: https://orcid.org/0000-0002-3782-8624)
- Cláudia Cristina Ferreira Vasconcelos (ORCID: https://orcid.org/0000-0003-0833-4024)
- Osvaldo J. M. Nascimento (ORCID: https://orcid.org/0000-0003-3516-485X)
- Carolina B. Moura
- Carina Tellaroli Spedo (ORCID: https://orcid.org/0000-0001-6627-9698)
- C Azevedo
- Jonadab dos Santos Silva (ORCID: https://orcid.org/0000-0002-4216-333X)
- Larissa Kelly Rodrigues Lopes
Institutions
- Universidade Federal Fluminense (BR)
- Universidade Federal de São Carlos (BR)
- Yale University (US)
- Universidade Federal do Estado do Rio de Janeiro (BR)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of Neuroimaging
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1111/jon.70081
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior