Aminophylline in acute exacerbation of COPD: Utility and treatment effects in hypercapnic respiratory failure (ACUTE): A pilot observational study

Aminophylline did not affect the length of hospital or ICU stay but improved hypercapnia and dyspnea severity in patients with refractory COPD exacerbations. We believe it should be used in severe acidotic COPD exacerbations unresponsive to conventional therapies, with an aim to correct hypercapnia.

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Publication Details

Journal
Lung India
Published
2025-09-01
DOI
https://doi.org/10.4103/lungindia.lungindia_582_24
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Aminophylline in acute exacerbation of COPD: Utility and treatment effects in hypercapnic respiratory failure (ACUTE): A pilot observational study

Aditya Satpati, Shyam K. Krishnan, Amrita Bhattacharyya, Ishita Chattopadhyay et al.
Lung India
Respiratory Support and Mechanisms
article

Aminophylline in acute exacerbation of COPD: Utility and treatment effects in hypercapnic respiratory failure (ACUTE): A pilot observational study

Aditya Satpati, Shyam K. Krishnan, Amrita Bhattacharyya, Ishita Chattopadhyay, Beauty Biswas, Arup Kumar Halder, Raja Dhar
article en

Abstract

Aminophylline did not affect the length of hospital or ICU stay but improved hypercapnia and dyspnea severity in patients with refractory COPD exacerbations. We believe it should be used in severe acidotic COPD exacerbations unresponsive to conventional therapies, with an aim to correct hypercapnia.

Lung IndiaVol. 42(5)
AMRI Hospitals (IN)
Openalex Percentile: Top 66%
Respiratory Support and Mechanisms
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