Super-Resolution Parameter Estimation Using Machine Learning-Assisted Spatial Mode Demultiplexing

We present the use of a light-weight machine learning (ML) model to estimate the separation and relative brightness of two incoherent light sources below the diffraction limit. We use a multi-planar light converter (MPLC) to implement spatial mode demultiplexing (SPADE) imaging. The ML model is trained, validated, and tested on data generated experimentally in the laboratory. The ML model accurately estimates the separation of the sources to up to two orders of magnitude below the diffraction limit when the sources are of comparable brightness, and provides accurate sub-diffraction separation resolution even when the sources differ in brightness by four orders of magnitude. The present results are limited by cross talk in the MPLC and support the potential use of ML-assisted SPADE for astronomical imaging below the diffraction limit.

Authors

Institutions

Publication Details

Journal
Sensors
Published
2025-09-01
DOI
https://doi.org/10.3390/s25175395
Citations
1
Primary Topic
Advanced Fluorescence Microscopy Techniques
Type
article
Field-Weighted Citation Impact
1.63

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Super-Resolution Parameter Estimation Using Machine Learning-Assisted Spatial Mode Demultiplexing

Kevin Vinsen, John Wallis, David R. Gozzard, Alex M. Frost et al.
1 citations
Sensors
Advanced Fluorescence Microscopy Techniques
1.63
article

Super-Resolution Parameter Estimation Using Machine Learning-Assisted Spatial Mode Demultiplexing

Kevin Vinsen, John Wallis, David R. Gozzard, Alex M. Frost, Benjamin P. Dix-Matthews, Nicolas Maron, J. L. Collier
article en
1 citations

Abstract

We present the use of a light-weight machine learning (ML) model to estimate the separation and relative brightness of two incoherent light sources below the diffraction limit. We use a multi-planar light converter (MPLC) to implement spatial mode demultiplexing (SPADE) imaging. The ML model is trained, validated, and tested on data generated experimentally in the laboratory. The ML model accurately estimates the separation of the sources to up to two orders of magnitude below the diffraction limit when the sources are of comparable brightness, and provides accurate sub-diffraction separation resolution even when the sources differ in brightness by four orders of magnitude. The present results are limited by cross talk in the MPLC and support the potential use of ML-assisted SPADE for astronomical imaging below the diffraction limit.

SensorsVol. 25(17)
Australian Research Council (AU), The University of Western Australia (AU), ARC Centre of Excellence for Engineered Quantum Systems (AU), International Centre for Radio Astronomy Research (AU)
Australian Government, Australian Research Council, Air Force Office of Scientific Research
Openalex Percentile: Top 12%
Advanced Fluorescence Microscopy Techniques
1.63
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.