Diffusivity anisotropy signature of the slowly expanding lesions predicts progression independent of relapse activity in multiple sclerosis
Definite SELs show distinct greater microstructural damage and are associated with PIRA, making their FA signature a potential predictor of MS progression.
Authors
- Eugenia Martínez‐Hernández (ORCID: https://orcid.org/0000-0002-8317-7068)
- Elianet Fonseca (ORCID: https://orcid.org/0000-0002-3613-3185)
- Salut Albà-Arbalat (ORCID: https://orcid.org/0000-0003-1662-2317)
- Sara Llufriú (ORCID: https://orcid.org/0000-0003-4273-9121)
- Eloy Martínez‐Heras (ORCID: https://orcid.org/0000-0001-9937-3162)
- Elisabeth Solana (ORCID: https://orcid.org/0000-0001-7973-2439)
- María Sepúlveda (ORCID: https://orcid.org/0000-0002-3078-645X)
- Pablo Villoslada (ORCID: https://orcid.org/0000-0002-8735-6119)
- Ferrán Prados (ORCID: https://orcid.org/0000-0002-7872-0142)
- Santiago Medrano-Martorell (ORCID: https://orcid.org/0000-0002-6586-7284)
- Alberto Calvi (ORCID: https://orcid.org/0000-0002-1953-2803)
- Baris Kanber (ORCID: https://orcid.org/0000-0003-2443-8800)
- Albert Saiz (ORCID: https://orcid.org/0000-0002-5793-8791)
- Elisabet López-Soley (ORCID: https://orcid.org/0000-0002-2183-8094)
- José María Cabrera‐Maqueda (ORCID: https://orcid.org/0000-0002-6984-1209)
- Francesc Vivó (ORCID: https://orcid.org/0000-0002-6409-1197)
- Yolanda Blanco (ORCID: https://orcid.org/0000-0002-1834-0498)
Institutions
- Universitat Oberta de Catalunya (ES)
- Universitat Pompeu Fabra (ES)
- National Institute for Health and Care Research (GB)
- Hospital Clínic de Barcelona (ES)
- University College London (GB)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1136/jnnp-2025-335884
- Citations
- 1
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Bristol-Myers Squibb Foundation
- Bristol-Myers Squibb
- Fundación BBVA
- European Committee for Treatment and Research in Multiple Sclerosis
- European Commission
- Banco Bilbao Vizcaya Argentaria
- Red Española de Esclerosis Múltiple
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- Instituto de Salud Carlos III
- Spanish National Plan for Scientific and Technical Research and Innovation