Monodentate/bidentate chiral Ph/Py-NO ligands: an unexpected switch of enantioselectivity in Friedel–Crafts alkylation of indoles and 2,3-dioxopyrrolidines
Key to the success of the switch of enantioselectivity is the existence of two different activation patterns. This study is the first example of a monodentate ligand in asymmetric catalytic FC alkylation.
Authors
- Guanjun Dong (ORCID: https://orcid.org/0000-0001-6185-1771)
- W. ZHANG (ORCID: https://orcid.org/0000-0002-3513-1866)
- Jing Lou (ORCID: https://orcid.org/0000-0002-7337-261X)
- Hui-Xian Jing
- Xiong‐Li Liu (ORCID: https://orcid.org/0000-0001-5188-6970)
- Dandan Liu (ORCID: https://orcid.org/0000-0002-2090-9217)
- Hong Cen (ORCID: https://orcid.org/0009-0005-7054-3195)
- Xifeng Zhu
- Dandan Pan (ORCID: https://orcid.org/0000-0001-7404-5269)
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Guizhou University (CN)
- Zhengzhou University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj02472b
- Citations
- 1
- Primary Topic
- Asymmetric Synthesis and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.94