Redefining Obesity in the Indonesian Population: The Critical Role of Waist‐to‐Height Ratio in Screening for Diabetes Mellitus and Hypertension

<b>Objectives:</b> Waist-to-height ratio (WHtR) is an alternative index to evaluate metabolic health and predict the risk of estimating the impact of adiposity on cardiometabolic diseases. Despite the significance, the diagnostic performance of WHtR has not been extensively investigated in large epidemiological studies in Indonesia. Therefore, this study aimed to investigate anthropometric indexes (body mass index [BMI], waist circumference [WC], waist-to-hip ratio [WHR], and WHtR) with the best clinically accurate and diagnostic performance in detecting the prevalence of diabetes mellitus (DM) and hypertension (HTN) in the Indonesian population. <b>Methods:</b> This study used a cross-sectional method to analyze big data of 7699 individuals from the Indonesian Family Life Survey. The diagnostic performance of each anthropometric index was analyzed using the receiver operating characteristics (ROC) curve model in the SPSS and MedCalc applications. Furthermore, the associations of anthropometric indexes with DM and HTN were evaluated using logistic regression adjusted for sociodemographic confounders. <b>Results:</b> WHtR showed the highest area under the curve (AUC) for detecting DM in men (0.731 [0.679-0.784]), as well as HTN in both men (0.650 [0.629-0.671]) and women (0.615 [0.598-0.633]). Although often negligible, the discrepancies had overlapping 95% confidence intervals with other indexes. WHtR also showed the strongest association with both DM (AOR [95% CI]: 3.166 [2.416-4.150]) and HTN (1.938 [1.703-2.206]). Lower cutoffs for BMI (22.72 kg/m<sup>2</sup>) and WC (83.35 cm) enhanced sensitivity for DM and HTN detection, particularly in men. <b>Discussion:</b> WHtR outperformed BMI, WC, and WHR in detecting DM and HTN in the Indonesian population. Additionally, lower cutoffs for overall (BMI) and abdominal obesity (WC) should be considered to enhance the sensitivity of anthropometric indexes in screening for cardiometabolic diseases in the population.

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Journal
Journal of Nutrition and Metabolism
Published
2025-01-01
DOI
https://doi.org/10.1155/jnme/5815261
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
0.00

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article

Redefining Obesity in the Indonesian Population: The Critical Role of Waist‐to‐Height Ratio in Screening for Diabetes Mellitus and Hypertension

Nurul Husna Mohd Shukri, Ratu Ayu Dewi Sartika, Fathimah S. Sigit, Jasrida Yunita et al.
Journal of Nutrition and Metabolism
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Redefining Obesity in the Indonesian Population: The Critical Role of Waist‐to‐Height Ratio in Screening for Diabetes Mellitus and Hypertension

Nurul Husna Mohd Shukri, Ratu Ayu Dewi Sartika, Fathimah S. Sigit, Jasrida Yunita, Pika Novriani Lubis, Edy Purwanto
article en

Abstract

<b>Objectives:</b> Waist-to-height ratio (WHtR) is an alternative index to evaluate metabolic health and predict the risk of estimating the impact of adiposity on cardiometabolic diseases. Despite the significance, the diagnostic performance of WHtR has not been extensively investigated in large epidemiological studies in Indonesia. Therefore, this study aimed to investigate anthropometric indexes (body mass index [BMI], waist circumference [WC], waist-to-hip ratio [WHR], and WHtR) with the best clinically accurate and diagnostic performance in detecting the prevalence of diabetes mellitus (DM) and hypertension (HTN) in the Indonesian population. <b>Methods:</b> This study used a cross-sectional method to analyze big data of 7699 individuals from the Indonesian Family Life Survey. The diagnostic performance of each anthropometric index was analyzed using the receiver operating characteristics (ROC) curve model in the SPSS and MedCalc applications. Furthermore, the associations of anthropometric indexes with DM and HTN were evaluated using logistic regression adjusted for sociodemographic confounders. <b>Results:</b> WHtR showed the highest area under the curve (AUC) for detecting DM in men (0.731 [0.679-0.784]), as well as HTN in both men (0.650 [0.629-0.671]) and women (0.615 [0.598-0.633]). Although often negligible, the discrepancies had overlapping 95% confidence intervals with other indexes. WHtR also showed the strongest association with both DM (AOR [95% CI]: 3.166 [2.416-4.150]) and HTN (1.938 [1.703-2.206]). Lower cutoffs for BMI (22.72 kg/m<sup>2</sup>) and WC (83.35 cm) enhanced sensitivity for DM and HTN detection, particularly in men. <b>Discussion:</b> WHtR outperformed BMI, WC, and WHR in detecting DM and HTN in the Indonesian population. Additionally, lower cutoffs for overall (BMI) and abdominal obesity (WC) should be considered to enhance the sensitivity of anthropometric indexes in screening for cardiometabolic diseases in the population.

Journal of Nutrition and MetabolismVol. 2025(1)
Universiti Putra Malaysia (MY), Universitas Airlangga (ID), University of Indonesia (ID), Universitas 17 Agustus 1945 Jakarta (ID), Universitas Hang Tuah (ID)
Universitas Indonesia
Openalex Percentile: Top 68%
Diabetes, Cardiovascular Risks, and Lipoproteins
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