Immunomodulatory effects of the combination of Korean red ginseng and Cervi Parvum Cornu via the MAPK pathway
Korean red ginseng (KRG) and Cervi Parvum Cornu (CPC) act synergistically to improve cyclophosphamide-induced immunosuppression in rats, as evidenced by restoration of lymphocyte numbers, enhanced NK cell cytotoxic activity, normalization of NK cell-related cytokine profiles, and activation of the MAPK signaling pathway.
Authors
- Ajay Vijayakumar (ORCID: https://orcid.org/0000-0002-3902-6473)
- Chang Won Kang (ORCID: https://orcid.org/0000-0002-9633-6574)
- Jun Hong Park (ORCID: https://orcid.org/0000-0001-8905-4125)
- Jong‐Hoon Kim (ORCID: https://orcid.org/0000-0003-3785-1207)
- BaiCheng Chen (ORCID: https://orcid.org/0009-0008-7491-3634)
Institutions
- Jeonbuk National University (KR)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1016/j.jgr.2025.08.010
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education
- National Research Foundation of Korea
- Korea Ginseng Corporation
- Korean Society of Ginseng