HIV Oral Pre-exposure Prophylaxis Effectiveness, Adherence, and Discontinuation in an Italian Multicentric Access Program: ItaPrEP Study
In this Italian oral PrEP program, the HIV incidence was lower than that observed in pivotal clinical trials in high-risk populations and close to that of observational real-life studies. Identifying fragile groups (youngest, low educational level, and chemsex users) and addressing barriers (free drugs and monitoring) are key to targeting strategies to improve oral PrEP implementation.
Authors
- Davide Moschese (ORCID: https://orcid.org/0000-0001-5901-6742)
- Roberto Rossotti (ORCID: https://orcid.org/0000-0003-4965-8789)
- Alessandro Tavelli (ORCID: https://orcid.org/0000-0001-5899-451X)
- Sandro Mattioli
- Claudio Maria Mastroianni (ORCID: https://orcid.org/0000-0002-1286-467X)
- Andrea Antinori (ORCID: https://orcid.org/0000-0003-2121-4684)
- Rozenn Esvan (ORCID: https://orcid.org/0000-0001-6127-0045)
- Antonella Cingolani (ORCID: https://orcid.org/0000-0002-3793-2755)
- Daniele Calzavara (ORCID: https://orcid.org/0000-0002-9999-891X)
- Lorenzo Badia (ORCID: https://orcid.org/0000-0001-5694-1158)
- Antonella Castagna (ORCID: https://orcid.org/0000-0002-8338-9714)
- Federico De Zottis (ORCID: https://orcid.org/0000-0001-9040-2000)
- Simone Lanini (ORCID: https://orcid.org/0000-0002-6743-4001)
- Valentina Mazzotta (ORCID: https://orcid.org/0000-0002-0240-7504)
- Silvia Nozza (ORCID: https://orcid.org/0000-0002-2673-2731)
- Massimo Cernuschi (ORCID: https://orcid.org/0000-0001-9229-7435)
- Giulia Micheli (ORCID: https://orcid.org/0000-0001-7996-8345)
- Daniele Tesoro
- Carlo Torti
- Giulia Marchetti (ORCID: https://orcid.org/0000-0002-4498-4828)
- Alessandra Oliva (ORCID: https://orcid.org/0000-0002-8124-7368)
- Alessandro Giacinta (ORCID: https://orcid.org/0009-0006-9031-619X)
- Marco Ridolfi
- Nicoletta Frattini
- S Cecere
- Alessandra Bianchi (ORCID: https://orcid.org/0000-0003-3937-4520)
- Roberto Repossi
- Rita Bellagamba
- Enrico Caruso (ORCID: https://orcid.org/0009-0004-7626-4704)
- Antonella d’Arminio Monforte
- Anna De Bona
Institutions
- University of Udine (IT)
- AOL (United States) (US)
- Vita-Salute San Raffaele University (IT)
- University of Pavia (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Center for Prevention and Treatment of Infections (US)
- CIMA Research Foundation (IT)
- Check Point (Israel) (IL)
- University of the Sacred Heart (JP)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1093/ofid/ofaf539
- Citations
- 8
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 11.17