Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk
Weekly administration of 50,000 IU of vitamin D for six months proved effective in reducing depressive symptoms and suicide risk while improving cardiovascular health markers, highlighting its promise as an accessible, low-cost adjunctive therapy in psychiatric and primary care settings.
Authors
- Ana Lúcia Figueiredo Porto (ORCID: https://orcid.org/0000-0001-5561-5158)
- Kátia Petribú (ORCID: https://orcid.org/0000-0002-8861-0238)
- Éverton Botelho Sougey (ORCID: https://orcid.org/0000-0003-0125-9201)
- Catarina S. Porto (ORCID: https://orcid.org/0000-0001-9695-2994)
- Eveline Barros Calado (ORCID: https://orcid.org/0000-0002-7079-2600)
- Brivaldo Markman Filho (ORCID: https://orcid.org/0000-0002-3068-0540)
- Andréa Bezerra de Melo da Silveira Lordsleem (ORCID: https://orcid.org/0000-0001-8212-0169)
- Nathalia Barbosa (ORCID: https://orcid.org/0000-0003-3295-5242)
- Francisco Alfredo Farias Bandeira (ORCID: https://orcid.org/0000-0003-0290-0742)
- Rayana Porpino Magalhães
- José Magalhães (ORCID: https://orcid.org/0000-0003-4808-8374)
- Cecília Magalhães Porto Lira (ORCID: https://orcid.org/0000-0001-6801-364X)
- Tatiana Silva (ORCID: https://orcid.org/0000-0002-7234-0042)
- R.B.C. Leão (ORCID: https://orcid.org/0000-0002-0292-2522)
- Aluísio Junio
Institutions
- Faculdade Frassinetti do Recife (BR)
- Faculdade Pernambucana de Saúde
- Fundação Oswaldo Cruz (BR)
- Universidade de Pernambuco (BR)
Publication Details
- Journal
- American Heart Journal Plus Cardiology Research and Practice
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1016/j.ahjo.2025.100599
- Citations
- 1
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47