Transcriptome sequencing of sheep hypothalamic tissue reveals the regulatory role of lncRNA in the mechanism of pubertal estrus initiation
Overall, this study demonstrates that lncRNAs regulate pubertal estrus initiation through ceRNA networks (e.g., LOC101105119-miR-106b-GNAQ) and hormone signaling, particularly the GnRH pathway, offering potential targets for sheep breeding.
Authors
- Xiaosheng Wang (ORCID: https://orcid.org/0000-0002-7199-7093)
- HuiPing Sun
- Yanan Peng
- Rong Xuan (ORCID: https://orcid.org/0000-0001-5548-432X)
- Wei Li (ORCID: https://orcid.org/0000-0001-9931-5990)
- Feng Xing (ORCID: https://orcid.org/0000-0003-0564-2187)
- Lingling Zhu (ORCID: https://orcid.org/0000-0002-4929-7103)
- RA Gu
- Qingshan Huang (ORCID: https://orcid.org/0009-0002-2705-9128)
Institutions
- Tarim University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fvets.2025.1594040
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00