SLC38A4 as a prognostic biomarker and correlated with immune infiltration in colorectal liver metastasis
Elevated SLC38A4 expression is correlated with a favorable prognosis in CRLM, likely through mechanisms involving metabolic reprogramming and immune infiltration. Thus, SLC38A4 may serve as both a prognostic biomarker and a potential biomarker for future therapeutic investigation, offering new precision medicine options for CRLM patients.
Authors
- Ying Liu (ORCID: https://orcid.org/0009-0004-8992-357X)
- Ningning Chen
- Xin Wei
- Weijia Wang (ORCID: https://orcid.org/0000-0001-5576-7979)
Institutions
- Shanxi Medical University (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1007/s12672-025-03509-9
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Xisike Clinical Oncology Research Foundation