Interleukin-4-mediated Pro-Regenerative Cellular Reprogramming in 3-dimensional Liver Culture
Our study highlights the potential of IL-4-driven modulation of the liver microenvironment, paving the way for cytokine-based therapeutic strategies to enhance immune-mediated hepatic regeneration.
Authors
- Sai Chung (ORCID: https://orcid.org/0000-0003-2684-7122)
- Satoshi Ogawa (ORCID: https://orcid.org/0000-0002-4790-546X)
- Seyyed Mehdi Jafari (ORCID: https://orcid.org/0000-0003-0483-7505)
- Sharon J. Hyduk (ORCID: https://orcid.org/0000-0003-2862-0300)
- Cornelia Thoeni (ORCID: https://orcid.org/0000-0002-7860-8724)
- Michael Cheng (ORCID: https://orcid.org/0000-0002-7841-3740)
- Cátia T. Perciani (ORCID: https://orcid.org/0000-0003-0377-1778)
- Manmeet Sekhon
- Diana Nakib (ORCID: https://orcid.org/0000-0002-4046-2109)
- Sonya A. MacParland (ORCID: https://orcid.org/0000-0002-8036-1425)
- Ian D. McGilvray (ORCID: https://orcid.org/0000-0003-4649-546X)
- Damra Camat (ORCID: https://orcid.org/0000-0001-8435-4073)
- Olivia I. Pezzutti (ORCID: https://orcid.org/0000-0002-1071-7916)
- Patricia Lumanto (ORCID: https://orcid.org/0009-0002-1155-9793)
- Yijia Liu
- Agata Bartczak
- Xue-Zhong Ma
- Justin Manuel
- Melina Kaltagian
- Fatima Altaf
Institutions
- University Health Network (CA)
- University of Toronto (CA)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101626
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00