Total and extracellular vesicle–bound plasma P-selectin as diagnostic biomarkers for acute deep vein thrombosis

The proportion of P-selectin bound to EVs in plasma was low and could not discriminate between patients with and without acute DVT. The diagnostic performance of total P-selectin, alone or in combination with D-dimer, was inferior to the diagnostic performance of D-dimer alone.

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Publication Details

Journal
Research and Practice in Thrombosis and Haemostasis
Published
2025-09-02
DOI
https://doi.org/10.1016/j.rpth.2025.103171
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Total and extracellular vesicle–bound plasma P-selectin as diagnostic biomarkers for acute deep vein thrombosis

Samantha Xavier, Casper J.E. Wahlund, Øyvind Øverli, Ellen Elisabeth Brodin et al.
Research and Practice in Thrombosis and Haemostasis
Blood Coagulation and Thrombosis Mechanisms
article

Total and extracellular vesicle–bound plasma P-selectin as diagnostic biomarkers for acute deep vein thrombosis

Samantha Xavier, Casper J.E. Wahlund, Øyvind Øverli, Ellen Elisabeth Brodin, John‐Bjarne Hansen, Nadezhda Latysheva, Thor Ueland, Sigrid Kufaas Brækkan, Omri Snir, Vårin Eiriksdatter Wikan, Christopher Antoun, Gholamreza Jafari Yeganeh
article en

Abstract

The proportion of P-selectin bound to EVs in plasma was low and could not discriminate between patients with and without acute DVT. The diagnostic performance of total P-selectin, alone or in combination with D-dimer, was inferior to the diagnostic performance of D-dimer alone.

Research and Practice in Thrombosis and HaemostasisVol. 9(7)
Oslo University Hospital (NO), University Hospital of North Norway (NO), University of Oslo (NO), Akershus University Hospital (NO), UiT The Arctic University of Norway (NO)
Openalex Percentile: Top 70%
Blood Coagulation and Thrombosis Mechanisms
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