Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients
To our knowledge, this is the first GWAS of FS, and our results support a genetic basis of FS. Future large-scale genetic research studies are needed to corroborate these findings and identify genetic variants associated with FS.
Authors
- Yen‐Chen Anne Feng (ORCID: https://orcid.org/0000-0003-2116-3645)
- Jocelyn F. Bautista
- Dennis Lal (ORCID: https://orcid.org/0000-0002-5173-9636)
- Veera M. Rajagopal (ORCID: https://orcid.org/0000-0002-5236-168X)
- Sanan Venkatesh (ORCID: https://orcid.org/0000-0002-3094-2731)
- Jakob Christensen (ORCID: https://orcid.org/0000-0002-9385-6435)
- Anders D. Børglum (ORCID: https://orcid.org/0000-0001-8627-7219)
- Imad Najm (ORCID: https://orcid.org/0000-0001-5192-2089)
- Georgios Voloudakis (ORCID: https://orcid.org/0000-0002-5729-632X)
- Jordan W. Smoller (ORCID: https://orcid.org/0000-0002-0381-6334)
- Jakob Grove (ORCID: https://orcid.org/0000-0003-2284-5744)
- Rebecca Birnbaum (ORCID: https://orcid.org/0000-0002-4206-4323)
- Costin Leu (ORCID: https://orcid.org/0000-0003-0598-3301)
- Péter Straub (ORCID: https://orcid.org/0009-0009-9693-8207)
- David Burstein (ORCID: https://orcid.org/0000-0003-0615-8178)
- Panos Roussos (ORCID: https://orcid.org/0000-0002-4640-6239)
- Slavina B. Goleva (ORCID: https://orcid.org/0000-0001-5177-9286)
- Lea K. Davis (ORCID: https://orcid.org/0000-0001-5143-2282)
- Robyn M. Busch
Institutions
- Broad Institute (US)
- National Institutes of Health (US)
- Allen Institute for Brain Science (US)
- Cleveland Clinic (US)
- National Taiwan University (TW)
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Massachusetts General Hospital (US)
- National Human Genome Research Institute (US)
- James J. Peters VA Medical Center (US)
- Lundbeck Foundation (DK)
- The University of Texas Health Science Center (US)
- Massachusetts Institute of Technology (US)
- Vanderbilt University Medical Center (US)
- The University of Texas Health Science Center at Houston (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1016/j.bpsgos.2025.100604
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00