The use of biodegradable temporising matrix for reconstructive salvage following full-thickness chest wall skin graft failure – A case report

NovoSorb biodegradable temporising matrix (BTM) has emerged as an effective material in the resurfacing of pathologies requiring extensive debridement or tissue loss, such as burns, necrotising soft tissue infections, and tumour excision. The use of BTM in cases of reconstructive salvage following graft failure is less well documented in the literature. We report a case of a 70-year-old female who initially underwent a wide local excision of a large chest wall basal cell carcinoma and full-thickness skin grafting of the resulting defect. Following graft failure and re-debridement, BTM application and consequent split-thickness grafting resulted in a successful reconstructive salvage and cosmetic outcome. This case reinforces the wide-ranging application of BTM in the reconstructive setting, and highlights the effectiveness of BTM in cases of graft failure requiring reconstructive salvage.

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Publication Details

Journal
JPRAS Open
Published
2025-09-02
DOI
https://doi.org/10.1016/j.jpra.2025.08.032
Primary Topic
Electrospun Nanofibers in Biomedical Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

The use of biodegradable temporising matrix for reconstructive salvage following full-thickness chest wall skin graft failure – A case report

Henning von Gregory, Baillie W. C. Ferris, Michael Auld
JPRAS Open
Electrospun Nanofibers in Biomedical Applications
article

The use of biodegradable temporising matrix for reconstructive salvage following full-thickness chest wall skin graft failure – A case report

Henning von Gregory, Baillie W. C. Ferris, Michael Auld
article en

Abstract

NovoSorb biodegradable temporising matrix (BTM) has emerged as an effective material in the resurfacing of pathologies requiring extensive debridement or tissue loss, such as burns, necrotising soft tissue infections, and tumour excision. The use of BTM in cases of reconstructive salvage following graft failure is less well documented in the literature. We report a case of a 70-year-old female who initially underwent a wide local excision of a large chest wall basal cell carcinoma and full-thickness skin grafting of the resulting defect. Following graft failure and re-debridement, BTM application and consequent split-thickness grafting resulted in a successful reconstructive salvage and cosmetic outcome. This case reinforces the wide-ranging application of BTM in the reconstructive setting, and highlights the effectiveness of BTM in cases of graft failure requiring reconstructive salvage.

JPRAS OpenVol. 46
Ipswich Hospital (AU), James Cook University (AU)
Openalex Percentile: Top 85%
Electrospun Nanofibers in Biomedical Applications
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