Comparing Mediterranean and Western Diets: Cognitive and Microbiota Effects in Middle-Aged Rats
A longer diet duration may be needed to elicit robust differences in cognitive function driven by the changes in microbiota and neurobiology. This study highlights that a short-term diet introduced in middle age has trending effects on cognitive performance but significantly impacts gut microbiota composition and gene expression of biomarkers of brain health.
Authors
- Elizabeth B. Engler-Chiurazzi (ORCID: https://orcid.org/0000-0002-7656-1192)
- Rebecca J. Solch-Ottaiano (ORCID: https://orcid.org/0000-0001-5752-9229)
- Blake Ouvrier (ORCID: https://orcid.org/0009-0006-9113-0215)
- Gregory Bix (ORCID: https://orcid.org/0000-0002-8969-9553)
- Saifudeen Ismael (ORCID: https://orcid.org/0000-0001-9976-0939)
- Demetrius M. Maraganore (ORCID: https://orcid.org/0000-0001-5351-3983)
- C Alex Harper (ORCID: https://orcid.org/0000-0002-8780-3986)
- Madison Prats
Institutions
- Tulane University (US)
Publication Details
- Journal
- Current Developments in Nutrition
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1016/j.cdnut.2025.107543
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Institutes of Health
- National Institute of General Medical Sciences