Investigation of Anticoagulant and Antiaggregant Drugs Used by Patients Diagnosed with Acute Stroke in the Emergency Department

Aim: The aim of this study was to analyze the anticoagulant & antiaggregant drugs used by patients diagnosed with ischemic stroke in their medical history. Materials and Methods: Our study was conducted retrospectively in the Emergency Department of Kayseri City Hospital. Patients over the age of 18 who were diagnosed with acute ischemic stroke and followed up between 01.01.2024-31.12.2024. The study was completed with 302 patients. Demographic data (age, gender), comorbidities, medications used by the patients were recorded and clinical outcomes were investigated. Results: The median age of the 302 patients included in the study was 72 years (IQRs: 62-79, min:30 max:97). 52.3% (n=158) of the patients were male and 47.7% (n=144) were female. While 11.9% (n=36) of the patients had a history of atrial fibrillation, 32.1% (n=97) of the patients had a history of antiplatelet or anticoagulant agent use. Acetylsalicylic acid was used by 14.2% (n=43), clopidogrel by 7.3% (n=22) and oral anticoagulant agents by 10.6% (n=32). There was a statistically significant difference in in-hospital mortality according to the antiplatelet, antiaggregant or anticoagulant agents used (p= 0.012). Conclusion: Accordingly, the mortality rate was lower in patients using acetylsalicylic acid compared to clopidogrel and oral anticoagulants.