Critical Commentary on ''Evaluation of in vitro antioxidative and protective effects of kefir on cyclophosphamide-upon oxidative stress and lung damage in rats

I read with great interest and attention article titled ''Evaluation of in vitro antioxidant and protective effects of kefir on cyclophosphamide-upon oxidative stress and lung damage in rats'' by Yıldız et al., which was published in the 5th volume 1st issue of Bingöl University Health Journal in 2024. In this letter, I would like to state that the protective effects of kefir on oxidative stress and tissue damage were successfully demonstrated in the study. However, the fact that only TOS, TAS and histopathological scoring analyses were performed in the study may be a limitation in terms of supporting the findings at the mechanism level. In order to increase the scientific rigor of the study, it may be suggested to add more detailed biochemical and molecular level analyses for antioxidant defense system (e.g. SOD, CAT, GPx activities) or inflammation markers in the future. I would like to thank the authors for their valuable contributions and look forward to future developments in this field.