Chemotaxis-related molecular markers underlying the immune disorder of psoriasis and ulcerative colitis: Preliminary analysis and verification

PSO and UC share chemokine abnormalities, including elevated levels of CCL20, CXCL1, and matrix metalloproteinase9, potentially linked to STAT1-expressing CD68 + macrophage infiltration. These shared molecular features suggest their potential as biomarkers for co-morbidity risk.

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Publication Details

Journal
Medicine
Published
2025-08-22
DOI
https://doi.org/10.1097/md.0000000000044022
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

Chemotaxis-related molecular markers underlying the immune disorder of psoriasis and ulcerative colitis: Preliminary analysis and verification

Qí Zhāng, Xia Qin, Youkun Lin, Wenyu Li et al.
Medicine
Psoriasis: Treatment and Pathogenesis
article

Chemotaxis-related molecular markers underlying the immune disorder of psoriasis and ulcerative colitis: Preliminary analysis and verification

Qí Zhāng, Xia Qin, Youkun Lin, Wenyu Li, Shuang Luo, Daiwen Liang
article en

Abstract

PSO and UC share chemokine abnormalities, including elevated levels of CCL20, CXCL1, and matrix metalloproteinase9, potentially linked to STAT1-expressing CD68 + macrophage infiltration. These shared molecular features suggest their potential as biomarkers for co-morbidity risk.

MedicineVol. 104(34)
Guangxi Medical University (CN), Qinhuangdao Glass Industry Research and Design Institute (China) (CN), First Affiliated Hospital of GuangXi Medical University (CN), S.P.E.C.I.E.S. (US)
Openalex Percentile: Top 75%
Psoriasis: Treatment and Pathogenesis
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