Point-of-Care Ultrasound Diagnosis of Diffuse Pulmonary Metastases: The Cannonball Sign

Cannonball pulmonary metastases are well characterized on radiographs and computed tomography of the chest, but their sonographic appearance on point-of-care ultrasound (POCUS) is not well described. We present a case of a 32-year-old man with a history of mixed germ cell tumor who presented with respiratory symptoms and tested positive for COVID-19. POCUS of the lung revealed numerous well-circumscribed subpleural lesions suggestive of metastatic disease, which helped differentiate them from COVID-19 pneumonia. Follow-up imaging confirmed diffuse metastases. This case highlights the potential utility of POCUS in detecting pulmonary metastases at the bedside and supports its growing role in acute care diagnostics.

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Publication Details

Journal
Annals of Internal Medicine Clinical Cases
Published
2025-09-01
DOI
https://doi.org/10.7326/aimcc.2025.0345
Primary Topic
Ultrasound in Clinical Applications
Type
article
Field-Weighted Citation Impact
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article

Point-of-Care Ultrasound Diagnosis of Diffuse Pulmonary Metastases: The Cannonball Sign

Hamna Javed, M. Sheikh, Mazin A.M. Elhassan, M.Y. Park et al.
Annals of Internal Medicine Clinical Cases
Ultrasound in Clinical Applications
article

Point-of-Care Ultrasound Diagnosis of Diffuse Pulmonary Metastases: The Cannonball Sign

Hamna Javed, M. Sheikh, Mazin A.M. Elhassan, M.Y. Park, William Latson
article en

Abstract

Cannonball pulmonary metastases are well characterized on radiographs and computed tomography of the chest, but their sonographic appearance on point-of-care ultrasound (POCUS) is not well described. We present a case of a 32-year-old man with a history of mixed germ cell tumor who presented with respiratory symptoms and tested positive for COVID-19. POCUS of the lung revealed numerous well-circumscribed subpleural lesions suggestive of metastatic disease, which helped differentiate them from COVID-19 pneumonia. Follow-up imaging confirmed diffuse metastases. This case highlights the potential utility of POCUS in detecting pulmonary metastases at the bedside and supports its growing role in acute care diagnostics.

Annals of Internal Medicine Clinical CasesVol. 4(9)
Saint Agnes Medical Center (US), California State University, Fresno (US)
Openalex Percentile: Top 73%
Ultrasound in Clinical Applications
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Point-of-Care Ultrasound Diagnosis of Diffuse Pulmonary Metastases: The Cannonball Sign — Hamna Javed, M. Sheikh, et al. · Annals of Internal Medicine Clinical Cases (2025) | TGRS Research Map | TGRS