A Mendelian randomization study of the associations between depression, anxiety and clinical conditions including thyroid nodules, flatulence, and irregular menstruation
MR analysis showed that depression causally worsens thyroid nodules and menstrual irregularities, while anxiety has no such association. Moreover, depression continuously impacts menstrual irregularities, even after anxiety adjustment. Our findings highlight the importance of mental health in managing physical health.
Authors
- Ju Jing (ORCID: https://orcid.org/0000-0002-8179-3625)
- Zheng Bi
- Lujie Wang (ORCID: https://orcid.org/0000-0002-9111-5713)
- Jinju Li (ORCID: https://orcid.org/0009-0009-7487-1953)
- Zhaohui Fang (ORCID: https://orcid.org/0000-0003-4181-2294)
Institutions
- Anhui University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1097/md.0000000000044041
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00