Concurrence of clozapine-induced diabetic ketoacidosis and neuroleptic malignant syndrome: A case report

DKA and NMS share various signs, such as fever, altered mental status, blood pressure instability, dyspnea, and tachycardia. Therefore, in patients receiving clozapine, the simultaneous occurrence of DKA and NMS should be considered. Additionally, clozapine-induced NMS may present in an atypical form; therefore, even in the absence of typical signs, such as rigidity and a rapid increase in CK, the possibility of NMS should be reconsidered.