Disturbances in the mucous membrane of the oral cavity of rats after consumption of excess sugar and aluminum chloride
The work studied inflammation markers (elastase and acid phosphatase activity), as well as an indicator of microbial contamination (urease activity) in the mucous membrane of the oral cavity of rats after consuming excess sugar and aluminum chloride. The influence of pathogenic factors on the activity of antioxidant protection and the degree of lipid peroxidation in the mucous membrane of the oral cavity of rats was studied. The results of the study indicate the development of inflammatory processes and the reproduction of opportunistic microbiota in the oral cavity of experimental groups of animals, which were more pronounced with the combined consumption of a large amount of sugar with an excess of aluminum. Suppression of antioxidant protection and, as a result, an outbreak of lipid peroxidation were observed.
Authors
- L. B. Tsevukh
- N. A. Kyrylenko
- О. А. Макаренко (ORCID: https://orcid.org/0000-0001-8029-4392)
- S. Stryzhak
Publication Details
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32782/1998-6475.2025.58.20
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00