Disturbances in the mucous membrane of the oral cavity of rats after consumption of excess sugar and aluminum chloride

The work studied inflammation markers (elastase and acid phosphatase activity), as well as an indicator of microbial contamination (urease activity) in the mucous membrane of the oral cavity of rats after consuming excess sugar and aluminum chloride. The influence of pathogenic factors on the activity of antioxidant protection and the degree of lipid peroxidation in the mucous membrane of the oral cavity of rats was studied. The results of the study indicate the development of inflammatory processes and the reproduction of opportunistic microbiota in the oral cavity of experimental groups of animals, which were more pronounced with the combined consumption of a large amount of sugar with an excess of aluminum. Suppression of antioxidant protection and, as a result, an outbreak of lipid peroxidation were observed.

Authors

Publication Details

Published
2025-01-01
DOI
https://doi.org/10.32782/1998-6475.2025.58.20
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Disturbances in the mucous membrane of the oral cavity of rats after consumption of excess sugar and aluminum chloride

L. B. Tsevukh, N. A. Kyrylenko, О. А. Макаренко, S. Stryzhak
Oral Health Pathology and Treatment
article

Disturbances in the mucous membrane of the oral cavity of rats after consumption of excess sugar and aluminum chloride

L. B. Tsevukh, N. A. Kyrylenko, О. А. Макаренко, S. Stryzhak
article en

Abstract

The work studied inflammation markers (elastase and acid phosphatase activity), as well as an indicator of microbial contamination (urease activity) in the mucous membrane of the oral cavity of rats after consuming excess sugar and aluminum chloride. The influence of pathogenic factors on the activity of antioxidant protection and the degree of lipid peroxidation in the mucous membrane of the oral cavity of rats was studied. The results of the study indicate the development of inflammatory processes and the reproduction of opportunistic microbiota in the oral cavity of experimental groups of animals, which were more pronounced with the combined consumption of a large amount of sugar with an excess of aluminum. Suppression of antioxidant protection and, as a result, an outbreak of lipid peroxidation were observed.

(58)
Openalex Percentile: Top 74%
Oral Health Pathology and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.