Analysis of racial differences in HER2 status and molecular subtype in grade 3 endometroid endometrial carcinoma
In stage I-III stage Gr3 EEC HER2 positivity (3 + ) was uncommon, but expression at the 2 + level was frequent, and did not differ by race. In this limited sample, there were no differences in distribution of TCGA subtype amongst patients with grade 3 EEC. Other causes should be explored to explain reported differences in outcomes in EEC by race.
Authors
- Jennifer A. Bennett (ORCID: https://orcid.org/0000-0001-8155-7131)
- Gini F. Fleming (ORCID: https://orcid.org/0000-0003-2845-4023)
- Yan Che (ORCID: https://orcid.org/0000-0002-4944-3860)
- Sarah Ackroyd (ORCID: https://orcid.org/0000-0001-9070-616X)
- S. Diane Yamada (ORCID: https://orcid.org/0000-0001-7922-4784)
- Gabrielle Sudilovsky
Institutions
- Gynecologic Oncology Group (US)
- University of Chicago (US)
Publication Details
- Journal
- Gynecologic Oncology Reports
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1016/j.gore.2025.101936
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00