Myeloid Cell Adhesion Molecule 1 (CADM1) Promotes Proinflammatory Signaling in Human Inflammatory Bowel Diseases
CADM1 is a mediator of proinflammatory signaling cascades in the colon and a potential therapeutic target for the IBDs.
Authors
- Lee‐Ching Zhu
- Nina C. Nishiyama (ORCID: https://orcid.org/0000-0003-2731-1987)
- Erin C. Steinbach (ORCID: https://orcid.org/0000-0002-6165-8928)
- Katelyn Clough (ORCID: https://orcid.org/0009-0000-4581-6327)
- Barbara J. Vilen (ORCID: https://orcid.org/0000-0003-0014-0022)
- Chandan Sona (ORCID: https://orcid.org/0000-0003-3107-016X)
- Bingfang Huan
- Michael T. Shanahan (ORCID: https://orcid.org/0000-0002-8411-4050)
- Monirath Hav (ORCID: https://orcid.org/0000-0001-8872-4588)
- Terrence S. Furey (ORCID: https://orcid.org/0000-0001-5546-9672)
- Huidong Chen (ORCID: https://orcid.org/0000-0003-1391-8198)
- Ayesh Awad
- Maloy Mangada
- Brinley F. Furey
- Máté Nagy (ORCID: https://orcid.org/0009-0007-8672-8228)
- Nathan K. VanLandingham (ORCID: https://orcid.org/0000-0001-8552-8987)
- Reza Rahbar (ORCID: https://orcid.org/0000-0002-6531-5922)
- Muneera R. Kapadia (ORCID: https://orcid.org/0000-0003-0382-880X)
- Matthew N. Poy (ORCID: https://orcid.org/0000-0002-4904-2426)
- Xinyun Bi (ORCID: https://orcid.org/0000-0003-4928-3964)
- Grace Lian (ORCID: https://orcid.org/0000-0002-4075-2739)
- Masanobu Komatsu (ORCID: https://orcid.org/0000-0001-7548-137X)
- Xin Yan (ORCID: https://orcid.org/0000-0002-8809-5803)
- Matthew R. Schaner (ORCID: https://orcid.org/0000-0001-8587-4679)
- Valerie Gartner (ORCID: https://orcid.org/0000-0001-5171-401X)
- Edward L. Barnes (ORCID: https://orcid.org/0000-0001-9894-8796)
- Alexandria J. Shumway (ORCID: https://orcid.org/0000-0003-2114-6845)
- Sophie Silverstein
- Surekha Bantumilli (ORCID: https://orcid.org/0000-0002-3213-6688)
- Si Fan (ORCID: https://orcid.org/0000-0003-1572-3677)
- Kimberly Darlington (ORCID: https://orcid.org/0000-0001-6890-9331)
- Shehzad Z. Sheikh (ORCID: https://orcid.org/0000-0002-4238-3674)
- Zahra Nur Khaled
- Akihiko Ito (ORCID: https://orcid.org/0000-0001-5783-5998)
- Praveen Sethupathy (ORCID: https://orcid.org/0000-0002-7983-239X)
- Yasuhiro Kikuchi
- Gerard Bain
- Timothy S. Sadiq
- Ginger E. Lau (ORCID: https://orcid.org/0000-0003-4647-7771)
- Meaghan Kennedy Ng
- Jamie Wong
- Dhawal Jain
- Muzaffar Akram
- Ezan A Chaudhry
Institutions
- University of North Carolina at Chapel Hill (US)
- Johns Hopkins University (US)
- Cornell University (US)
- Rex Hospital (US)
- Johns Hopkins All Children's Hospital (US)
- Geron (United States) (US)
- NKT Therapeutics (United States) (US)
- Entasis Therapeutics (United States) (US)
- University of Rostock (DE)
- Pacific Biosciences (United States) (US)
- Kindai University (JP)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101618
- Citations
- 1
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- American Diabetes Association Research Foundation
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases
- Leona M. and Harry B. Helmsley Charitable Trust
- Crohn's and Colitis Foundation
- National Cancer Institute
- National Institute of Diabetes and Digestive and Kidney Diseases