Identification of ATG4B and NLRP1 as M1 Macrophage-Activating-Related Plasma Proteins in Systemic Lupus Erythematosus via Multi-Omics Approaches
Our multi-omics and molecular dynamics simulation identified ATG4B and NLRP1 as potential SLE biomarkers and therapeutic targets, with implications for M1 macrophage-driven pathogenesis.
Authors
- Meng He
- Wanxin Tang (ORCID: https://orcid.org/0000-0001-6709-5591)
- Lei Chen (ORCID: https://orcid.org/0009-0003-4906-5163)
- Jianming Du (ORCID: https://orcid.org/0000-0003-0501-8616)
- Yujie Zuo
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1159/000548167
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00