Additional Effects of Faricimab in Aflibercept Low-Responders: Retinal Morphology and Function in Eyes with Neovascular Age Related Macular Degeneration Following a Switch Between Two Anti-VEGF Agents

An initial loading dose could be beneficial to elongate Faricimab's additional effect of reducing retinal swelling in eyes with nAMD and previous low-response to Aflibercept. Serous and drusenoid PEDs seem to benefit more than fibrovascular PEDs. A high amount of intraretinal HRF in patients with PED was a sign for good respondence to Faricimab.

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Publication Details

Journal
Clinical ophthalmology
Published
2025-09-01
DOI
https://doi.org/10.2147/opth.s530355
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

Additional Effects of Faricimab in Aflibercept Low-Responders: Retinal Morphology and Function in Eyes with Neovascular Age Related Macular Degeneration Following a Switch Between Two Anti-VEGF Agents

Haidar Khalil, Jan Rothbächer, Matthias Bolz, Markus Eidherr
1 links
Clinical ophthalmology
Retinal Diseases and Treatments
article

Additional Effects of Faricimab in Aflibercept Low-Responders: Retinal Morphology and Function in Eyes with Neovascular Age Related Macular Degeneration Following a Switch Between Two Anti-VEGF Agents

Haidar Khalil, Jan Rothbächer, Matthias Bolz, Markus Eidherr
article en

Abstract

An initial loading dose could be beneficial to elongate Faricimab's additional effect of reducing retinal swelling in eyes with nAMD and previous low-response to Aflibercept. Serous and drusenoid PEDs seem to benefit more than fibrovascular PEDs. A high amount of intraretinal HRF in patients with PED was a sign for good respondence to Faricimab.

Clinical ophthalmologyVol. Volume 19
Johannes Kepler University of Linz (AT), Kepler Universitätsklinikum (AT)
Openalex Percentile: Top 65%
Retinal Diseases and Treatments
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