Comparison of computed tomography coronary angiography (CTCA) alone vs. CTCA with selective FFRCT in patients presenting with stable chest pain: a FORECAST trial substudy
In this prespecified FORECAST substudy of patients whose clinicians preferred CTCA as the first test prior to randomization, the CTCA ± FFR<sub>CT</sub> strategy, when compared with CTCA alone, was cost-neutral in the UK and associated with significantly fewer additional non-invasive tests. Time to final management plan was also significantly lower in the experimental arm [median 64 days (IQR 48-110) vs. 75 days (55-126) in the standard care CTCA arm (<i>P</i> < 0.001)].
Authors
- Mark A. Hlatky (ORCID: https://orcid.org/0000-0003-4686-9441)
- Sam Wilding (ORCID: https://orcid.org/0000-0003-4184-2821)
- Nick Curzen (ORCID: https://orcid.org/0000-0001-9651-7829)
- Hussein Bashar (ORCID: https://orcid.org/0000-0001-8256-5168)
- Lavinia Gabara (ORCID: https://orcid.org/0000-0003-1729-3391)
- Mohamed Abouelasaad
- Campbell Rogers (ORCID: https://orcid.org/0000-0003-3955-7650)
- Ahmed Elserwey (ORCID: https://orcid.org/0000-0002-8274-8981)
- Pamela S. Douglas (ORCID: https://orcid.org/0000-0001-9876-4049)
- Mohamed Kira
- Zoe Nicholas (ORCID: https://orcid.org/0000-0003-4674-3259)
Institutions
- Duke University (US)
- Southampton General Hospital (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- NIHR Southampton Biomedical Research Centre (GB)
- Duke Medical Center (US)
- HeartFlow (United States) (US)
- NIHR Evaluation Trials and Studies Coordinating Centre (GB)
- Stanford Medicine (US)
- University of Southampton (GB)
- Stanford University (US)
Publication Details
- Journal
- European Heart Journal - Imaging Methods and Practice
- Published
- 2025-08-30
- DOI
- https://doi.org/10.1093/ehjimp/qyaf113
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Servier