Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain
This cross-sectional study found that timely receipt of opioids was associated with a reduction in hospitalizations for SCD pain. The largest decrease in hospitalization was achieved with the first dose within 60 minutes and the second dose within 30 minutes; however, longer second-dose durations were associated with reduced hospitalizations.
Authors
- Keli D. Coleman (ORCID: https://orcid.org/0000-0002-7135-9569)
- Irina Topoz
- Allison A. King (ORCID: https://orcid.org/0000-0002-1951-6176)
- Selena Hariharan (ORCID: https://orcid.org/0000-0002-5519-1989)
- Ibrahim Gwarzo (ORCID: https://orcid.org/0000-0002-0794-179X)
- Blake Nielsen
- Jacqueline B. Corboy (ORCID: https://orcid.org/0000-0002-6428-2444)
- Alexis A. Thompson (ORCID: https://orcid.org/0000-0003-4961-8103)
- Claudia R. Morris (ORCID: https://orcid.org/0000-0001-6019-2858)
- David C. Brousseau (ORCID: https://orcid.org/0000-0001-7995-6504)
- Ana A. Baumann (ORCID: https://orcid.org/0000-0002-4523-0147)
- Andrew Campbell (ORCID: https://orcid.org/0000-0002-8829-0043)
- Lawrence J. Cook (ORCID: https://orcid.org/0000-0001-9085-0428)
- Charles T. Quinn (ORCID: https://orcid.org/0000-0002-2372-2175)
- Rachelle Nuss (ORCID: https://orcid.org/0000-0001-8756-1967)
- Robert I. Liem (ORCID: https://orcid.org/0000-0003-2057-3749)
- Morgan Wurtz
- Anthony Villella (ORCID: https://orcid.org/0000-0002-5085-8107)
- Kenneth McKinley (ORCID: https://orcid.org/0000-0003-4624-5778)
- Angela M. Ellison
- Amanda M. Brandow (ORCID: https://orcid.org/0000-0001-9396-0470)
- Elizabeth R. Alpern (ORCID: https://orcid.org/0000-0001-7887-3563)
- Warren D. Frankenberger (ORCID: https://orcid.org/0000-0003-3794-2141)
Institutions
- Northwestern University (US)
- Children's Hospital of Wisconsin (US)
- Cincinnati Children's Hospital Medical Center (US)
- Lurie Children's Hospital (US)
- Nationwide Children's Hospital (US)
- Children's Hospital of Philadelphia (US)
- Children's National (US)
- Thomas Jefferson University (US)
- Emory University (US)
- Washington University in St. Louis (US)
- University of Utah (US)
- Children's Hospital Colorado (US)
- Nemours Children's Health System (US)
- Center for Cancer and Blood Disorders (US)
- Lurie Children's Hospital (US)
- Children's Healthcare of Atlanta (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Cincinnati Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- JAMA Pediatrics
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1001/jamapediatrics.2025.2967
- Citations
- 2
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.25