Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia

EA improved cognitive dysfunction in VD rats, and its mechanism may be related to the regulation of protein lactylation modifications in the hippocampal tissue. It involves multiple targets and pathways and may be related to the enhanced level of Vdac3 lactylation modification.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-09-02
DOI
https://doi.org/10.3389/fneur.2025.1629474
Primary Topic
Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia

Xinran Li, Hongxu Zhao, Zhongren Sun, Lin Wu et al.
Frontiers in Neurology
Neurological Disorders and Treatments
article

Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia

Xinran Li, Hongxu Zhao, Zhongren Sun, Lin Wu, Ruiqi Qin, Xiaoqing Su, Junfeng Li, Yi Miao, Yinghua Chen, Tong Wu, Wei Sun, Yuanyu Song, H. Wang
article en

Abstract

EA improved cognitive dysfunction in VD rats, and its mechanism may be related to the regulation of protein lactylation modifications in the hippocampal tissue. It involves multiple targets and pathways and may be related to the enhanced level of Vdac3 lactylation modification.

Frontiers in NeurologyVol. 16
Heilongjiang University of Chinese Medicine (CN), First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 71%
Neurological Disorders and Treatments
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