E2F5 Accelerates Vascular Smooth Muscle Cells Phenotype Switching in Diabetic Atherosclerosis through Activating Wnt/β-Catenin Pathway
E2F5 is an injurious factor in the pathogenesis of DAS, and the downregulation of E2F5 could repress VSMCs phenotype switching through inactivating Wnt/β-catenin pathway, and ultimately inhibit the progression of DAS.
Authors
- Qun Xu
- Mingxue Di (ORCID: https://orcid.org/0000-0003-3752-9904)
- Lin Sun (ORCID: https://orcid.org/0000-0003-2218-0527)
- Guang Yang (ORCID: https://orcid.org/0000-0003-3049-4200)
- Jie Wang
Institutions
- Weifang Medical University (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Diabetes & Metabolism Journal
- Published
- 2025-09-01
- DOI
- https://doi.org/10.4093/dmj.2024.0588
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province