Feasibility and clinical and implementation effectiveness of an adapted early warning signs and symptoms intervention for the early detection of childhood cancer in Cameroon and Kenya: protocol for a quasi-experimental, hybrid type 2 implementation e
This study has received ethical approval from The Hospital for Sick Children (REB # 1000080092) and all participating sites. We have received National Ethical Clearance from the Cameroon Ethical Board (#1699) and Regional Administrative Authorizations from our piloting regions (Centre and West). We have also received ethical clearance from Kenyatta National Hospital (KNH) (ERB# KNH-ERC/RR/955) and our National Commission for Science, Technology and Innovation in Kenya licence from the counties we are piloting in Kenya. As clinical data will be collected from existing health registries and patient charts, patient consent will not be required; however, we will obtain consent from all members of the leadership implementation teams and operational implementation teams for their participation in the implementation meetings and from all individuals participating in the semistructured interviews. We will disseminate findings to build awareness and share findings among various target audiences: (1) key county and regional parties (eg, clinical societies, advocacy groups, country MOHs and regional bodies such as the East African Community, Economic Community of West African States); (2) international bodies such as the WHO; and (3) the academic community.
Authors
- Glenn Mbah Afungchwi (ORCID: https://orcid.org/0000-0002-5512-9624)
- Alexandra Martiniuk (ORCID: https://orcid.org/0000-0003-1368-8206)
- Melanie A. Barwick (ORCID: https://orcid.org/0000-0002-2478-604X)
- Nathan P. Ward (ORCID: https://orcid.org/0000-0003-4920-0081)
- Fongang Che Landis
- Sumit Gupta (ORCID: https://orcid.org/0000-0003-1334-3670)
- Avram Denburg (ORCID: https://orcid.org/0000-0003-0039-0742)
- Melinda Chelva
- Maureen King’e
- Jessie Nyokabi Githanga
- Angèle Pondy
- Hayle Noh
Institutions
- University of Nairobi (KE)
- The University of Sydney (AU)
- Université de Yaoundé I (CM)
- Hospital for Sick Children (CA)
- UNSW Sydney (AU)
- World Cancer Research Fund International (GB)
- SickKids Foundation (CA)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-094502
- Primary Topic
- Health Policy Implementation Science
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Institutes of Health Research