Prevalence of <i>Plasmodium </i>species in asymptomatic individuals in North-Eastern South Africa: 2018 - 2019
A relatively high asymptomatic Plasmodium infection prevalence was observed in the study area, with P. ovale being the most prevalent species. Therefore, P. ovale infections may be missed with the Plasmodium RDT. R21 and RTS,S vaccines may not offer protection against P. ovale in the study area. Further research is needed to link asymptomatic infections in the study area and the periodic malaria outbreaks, and to determine the significance of the novel SNP in the Pfk13 gene.
Authors
- Sara Krivacsy
- Rebecca Dillingham (ORCID: https://orcid.org/0000-0001-9748-1215)
- Piper E. Shifflett
- Elizabeth T. Rogawski McQuade (ORCID: https://orcid.org/0000-0002-4942-3747)
- Pascal Bessong (ORCID: https://orcid.org/0000-0003-0561-272X)
- Darwin J. Operario (ORCID: https://orcid.org/0000-0002-3815-9311)
- Mukhethwa Munzhedzi (ORCID: https://orcid.org/0000-0003-1082-0881)
- Jennifer L. Güler (ORCID: https://orcid.org/0000-0001-6301-4563)
Institutions
- Emory University (US)
- University of Virginia Health System (US)
- University of Virginia (US)
- University of Venda (ZA)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- South African Medical Journal
- Published
- 2025-09-02
- DOI
- https://doi.org/10.7196/samj.2025.v115i8.2273
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- University of Venda
- National Institutes of Health
- Fogarty International Center