Systematic analysis and mechanistic investigation of cardiac adverse events associated with antibody–drug conjugates using FAERS database
This study underscores the importance of recognizing and managing the cAEs associated with ADC therapy. Our findings provide a nuanced understanding of the burden, risk factors, and potential biological mechanisms of ADC-related cAEs, which can inform clinical decision-making and guide the development of safer and more effective ADC therapies.
Authors
- Xiaohan Zheng
- Yongzhen Song
- Lei Cao (ORCID: https://orcid.org/0000-0002-8666-0127)
- Liuying Wang (ORCID: https://orcid.org/0000-0002-1701-9416)
- Yaru Wang (ORCID: https://orcid.org/0000-0001-8300-0847)
- Xuan Zhang (ORCID: https://orcid.org/0000-0002-4649-7716)
- Huimin Zhang (ORCID: https://orcid.org/0000-0002-5359-1399)
- Shi Li (ORCID: https://orcid.org/0000-0003-4780-2863)
- Qi Zhang (ORCID: https://orcid.org/0000-0002-6096-0690)
- Yong Cao
- Kaiyuan Ge
Institutions
- Harbin Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1097/js9.0000000000003314
- Citations
- 1
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05