Formulation and quality validation of an antiseptic ointment from Jacaranda Flower [Jacaranda mimosifolia]: A biochemical and microbiological approach

This study evaluated the implementation of quality parameters for the development of an antiseptic ointment made with Jacaranda flower [J. mimosifolia] extract. Mexican Official Standards [NOM-248-SSA1-2011, NOM-259-SSA1-2022, and NOM-073-SSA1-2015] were applied to ensure good manufacturing practices, microbiological control, and stability. The optimal formulation included petroleum jelly, coconut oil, and menthol, resulting in a stable and safe composition with proven antimicrobial effectiveness. Organoleptic, pH, and microbiological viability studies were conducted for 21 days under three different environmental conditions. Results showed absence of pathogens such as Staphylococcus aureus, E. coli, and fungi, while maintaining physicochemical properties. It is concluded that the developed formulation is safe, effective, and suitable for topical application, with potential use in minor injuries and dermatological diseases.