Gut microbiota characteristics and therapeutic effects of fecal microbiota transplantation in children with autism spectrum disorder in central China: a combined cross-sectional and prospective study
A simplified pediatric donor FMT protocol effectively modulates gut microbiota composition and alleviates both behavioral and gastrointestinal symptoms in children with ASD. This strategy demonstrates feasibility for clinical translation, highlighting microbiota-targeted therapy as a promising intervention for ASD.
Authors
- Jingyi Fan (ORCID: https://orcid.org/0000-0002-4624-5287)
- Teng Xu (ORCID: https://orcid.org/0000-0002-5169-1425)
- Rui Wu (ORCID: https://orcid.org/0009-0004-0054-6553)
- Heyun Gao
- Yanna Cai (ORCID: https://orcid.org/0000-0001-8734-5949)
- Wen Zhang (ORCID: https://orcid.org/0000-0001-5221-2628)
- Yunkai Guo
- Hexiao Shen (ORCID: https://orcid.org/0009-0000-5142-2180)
- Yongling Lv
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Hubei University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fped.2025.1648471
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Wuhan University
- Zhongnan Hospital of Wuhan University