China Expert consensus on the application of metagenomic next-generation sequencing for the etiological diagnosis of infections in hematological disorders (2024)
Infections are frequent complications in patients with hematological disorders, and pathogen diagnosis remains challenging. Metagenomic next-generation sequencing (mNGS) is an unbiased high-throughput technology that has been widely applied in the diagnosis of infectious diseases. However, to date, there are no established international guidelines or expert consensuses regarding the use of mNGS to diagnose infections in patients with hematologic disorders. The Anti-Infection Study Group of the Chinese Society of Hematology invited experts in the fields of hematology, microbiology, and mNGS technology to draft an expert consensus focused on clinical indications, sample collection, quality control, and interpretation of results. This consensus will likely contribute to clarifying the medical indications for mNGS testing, optimizing the interpretation of reports, and becoming an inspiration for global practice.
Authors
- Jiong Hu (ORCID: https://orcid.org/0000-0001-8266-0886)
- Hui Wang (ORCID: https://orcid.org/0000-0001-9220-0357)
- Ren Lin (ORCID: https://orcid.org/0000-0002-9402-0883)
- Fen Huang
- Chunyan Ji (ORCID: https://orcid.org/0000-0003-4438-1768)
- Aibin Liang (ORCID: https://orcid.org/0000-0002-8978-1987)
- Zunmin Zhu (ORCID: https://orcid.org/0000-0002-6635-7454)
- Xi Zhang (ORCID: https://orcid.org/0000-0003-1340-7128)
- Chunhui Xu (ORCID: https://orcid.org/0000-0002-3836-3179)
- Heng Mei (ORCID: https://orcid.org/0000-0001-7941-2443)
- Sizhou Feng (ORCID: https://orcid.org/0000-0002-8587-3446)
- Zhijian Xiao (ORCID: https://orcid.org/0000-0002-1099-4489)
- Ting Yang (ORCID: https://orcid.org/0000-0001-8872-8749)
- Xiaohui Zhang
- Weili Zhao (ORCID: https://orcid.org/0000-0002-6834-1616)
- Aining Sun (ORCID: https://orcid.org/0000-0002-6355-9595)
- Yehui Tan (ORCID: https://orcid.org/0000-0002-6378-2156)
- Yu Hu (ORCID: https://orcid.org/0000-0002-2815-4568)
- Jianda Hu (ORCID: https://orcid.org/0000-0002-4438-2544)
- Ting Niu (ORCID: https://orcid.org/0000-0003-1580-1014)
- Jun Ma (ORCID: https://orcid.org/0000-0003-3412-7766)
- Jianxiang Wang (ORCID: https://orcid.org/0000-0001-9437-9151)
- Xin Li (ORCID: https://orcid.org/0000-0001-8948-6331)
- Cheng Zhang (ORCID: https://orcid.org/0000-0003-1020-0850)
- Xiao‐Jun Huang (ORCID: https://orcid.org/0000-0002-3636-4813)
- Wenbin Qian (ORCID: https://orcid.org/0000-0002-9817-6674)
- Peihua Lu (ORCID: https://orcid.org/0000-0002-6331-7369)
- Yongping Song (ORCID: https://orcid.org/0000-0002-1659-7441)
- Zhuanzhen Zheng
- Yu Wang (ORCID: https://orcid.org/0000-0003-0202-3225)
- Jimin Shi (ORCID: https://orcid.org/0000-0003-0950-0581)
- Qifa Liu
- Ye Bai
- Depei Wu (ORCID: https://orcid.org/0000-0002-0050-9830)
- Yanqiu Han
- Jian Ouyang (ORCID: https://orcid.org/0009-0009-6821-0243)
Institutions
- Tongji University (CN)
- Fujian Medical University (CN)
- Union Hospital (HK)
- Central South University (CN)
- Army Medical University (CN)
- Shanxi Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Jilin University (CN)
- Peking University (CN)
- Sichuan University (CN)
- Ruijin Hospital (CN)
- Soochow University (CN)
- West China Hospital of Sichuan University (CN)
- Nanjing Drum Tower Hospital (CN)
- Xinqiao Hospital (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Peking University People's Hospital (CN)
- First Hospital of Jilin University (CN)
- Henan Provincial People's Hospital (CN)
- Second Hospital of Shanxi Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
- Henan Cancer Hospital (CN)
- Institute of Hematology & Blood Diseases Hospital (CN)
- First Affiliated Hospital of Soochow University (CN)
- Third Xiangya Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Tongji Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Inner Mongolia Medical University (CN)
- Huazhong University of Science and Technology (CN)
- Southern Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Blood Science
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1097/bs9.0000000000000241
- Citations
- 1
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 1.35